Famosan 10 mg
Famotidinum 10 mg in 1 coated tablet
Antiulceric agent, H2-receptor antagonist (ATC code: A02BA03)
The drug is used for the short-term and symptomatic treatment of heartburn, gastric hyperacidity, and nausea. It can be taken by adults over 18 years of age without consulting a physician. Children under 16 years of age may take the drug only if recommended by a physician.
Famotidine, a histamine H2-receptor antagonist with high binding specificity, inhibits diurnal and nocturnal gastric secretion, both basal and stimulated. It thus produces a decrease in both acidity and volume of gastric juice. Famotidine shows high efficacy and prolonged action. It does not interfere with cytochrome P-450, does not inhibit the oxidative biotransformation of other drugs and does not reduce alcohol-dehydrogenase activity.
Pharmaceutical formCoated tablets
Posology and method of administration
Unless a physician recommends otherwise, adults usually take 1 tablet in case of complaints. This dose should bring relief for a period of about 9 hours. In the course of 24 hours, two tablets may be taken. Tablets are swallowed unchewed with sufficient fluid.
Hypersensitivity to famotidine and other H2-receptor antagonists, malignant nature of ulcer disease, children under 16 years of age (due to lack of experience), lactation. Therapeutic urgency should be considered during pregnancy, caution is required in patients with severe renal and hepatic impairment.
Clinically relevant negative interactions with other drugs are not known. Famotidine affects neither the absorption of other drugs in the intestine nor their enzymatic biotransformation in the liver. By decreasing the acidity of gastric contents, H2-receptor antagonists decrease the absorption of ketoconazole and itraconazole. Famotidine should therefore be administered at least 2 hours after the administration of these drugs. Antacids (magnesium hydroxide and aluminum hydroxide) decrease the absorption of famotidine. For this reason they should be administered 1–2 hours after the administration of famotidine.
Famotidine is very well tolerated. Occasionally, headaches, vertigo, dry mouth, nausea, flatulence, constipation, diarrhoea, loss of appetite, allergic skin reactions may occur. Sporadically, there may be an increase in liver enzymes, leucopenia and thrombocytopenia.
Special warnings and precautions for use
Therapy should not exceed 5 days without consulting a physician. Patients with diagnosed ulcer disease, severe renal or hepatic disorders, middle-aged and elderly patients who have suffered indigestion-related weight loss (dyspeptic syndrome), swallowing difficulties and patients concomitantly using other medicinal products must consult a physician regarding the suitability of use of this product. As Famosan contains lactose, is not suitable for patients with Lapp-lactase deficiency or glucose and galactose malabsorption.
Contents of container
10 coated tablets
Package available in the Czech Republic
10 coated tablets
For more detailed product information, see the Summary of Product Characteristics.